AKR1C4 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A7430-20, A7430-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 37kDa
Observed Molecular Weight: 37kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 1109
SWISS: P17516
Alternate Names: C11; CDR; DD4; CHDR; DD-4; HAKRA; 3-alpha-HSD; AKR1C4
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Lipid Metabolism.
NCBI Alias: AKR1C4
Research Use Only