Product Description

Akt (pan)Rabbit Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA12276-50, RA12276-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: AKT1 gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT proteins all have an N-terminal pleckstrin homology domain, a serine/threonine-specific kinase domain and a C-terminal regulatory domain. These proteins are phosphorylated by phosphoinositide 3-kinase (PI3K). AKT/PI3K forms a key component of many signalling pathways that involve the binding of membrane-bound ligands such as receptor tyrosine kinases, G-protein coupled receptors, and integrin-linked kinase. These AKT proteins therefore regulate a wide variety of cellular functions including cell proliferation, survival, metabolism, and angiogenesis in both normal and malignant cells.

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF, ELISA

Alternate Names: AKT1/AKT2/AKT3

Clonality: Monoclonal

Dilution: IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;Note:For IHC, wesuggest antigen retrieval with TE buffer pH 9.0

Storage: -20°C/1 year

Condition: Liquid in PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA

Human Gene ID: 207;208;10000

Protein Molecular Weight（KDa): 55

Molecular Weight: 55

Research Use Only