AL7A1 rabbit pAb - ES18406

AL7A1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES18406-50, ES18406-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human AL7A1 AA range: 229-279

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 501

Human SWISS Prot NO: P49419

Subcellular Location: [Isoform 2]: Cytoplasm, cytosol. Nucleus.; [Isoform 1]: Mitochondrion.

Research Use Only