ALAS1 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS6320-50, BS6320-100
Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P13196
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IF/ICC
All Applications: WB,1:500 - 1:2000 | IF/ICC,1:50 - 1:200
Background: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Polyclonal Antibodies
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Immunofluorescence analysis of HeLa cells using ALAS1 antibody. Blue: DAPI for nuclear staining.
Alternative Name: ALAS1; ALAS; ALAS-H; ALAS3; ALASH; MIG4
Immunogen: Recombinant fusion protein of human ALAS1(NP_954635.1).
Conjugate: Unconjugated
Modification: Unmodified