ALDH2 Mouse Monoclonal Antibody - RA10749

ALDH2 Mouse Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA10749-50, RA10749-100

Citations, Manuals and MSDS Available upon request.

Background: aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2) Homo sapiens This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform,

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat; Monkey; Hamster

GeneID (Human): 217

Protein MW (KDa): 56

SWISS: P05091

Source: Mouse

Research Use Only