ALDH3B2 Polyclonal Antibody
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Catalogue Numbers: BS60095-50, BS60095-100
Sizes: 50µl, 100µl
Swiss-Prot: P48448
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC
Background: ALDH3B2 (aldehyde dehydrogenase 3 family, member B2), also known as ALDH8, is a 385 amino acid protein that belongs to the ALDH family and is involved in the pathway of alcohol metabolism. Expressed in salivary gland tissue, ALDH3B2 functions to catalyze the NADP+-dependent conversion of an aldehyde into an acid. The gene encoding ALDH3B2 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Specificity: ALDH3B2 polyclonal antibody detects endogenous levels of ALDH3B2 protein.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of ALDH3B2 polyclonal antibody at 1:500 dilution
Lane 1: Hela whole cell lysate
Lane 2: Raw264.7 whole cell lysate
Lane 3: H9C2 whole cell lysate, Immunohistochemistry (IHC) analyzes of ALDH3B2 pAb in paraffin-embedded human liver carcinoma tissue at 1:50,showing cytoplasm and membrane staining.Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.
Bioworld Molecular Weight: ~ 43 kDa
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Alternative Name: Aldehyde dehydrogenase family 3 member B2; Aldehyde dehydrogenase 8; ALDH3B2; ALDH8
Immunogen: A synthetic peptide corresponding to residues in Human ALDH3B2.
Conjugate: Unconjugated
Modification: Unmodified