alpha Smooth Muscle Actin (3G2) Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB3218-50, MB3218-100
Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Swiss-Prot: P62736
Host: Mouse
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-F, IHC-P, ICC/IF
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Background: Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG1
Bioworld Molecular Weight: Calculated MW: 42 kDa; Observed MW: 42 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Immunohistochemistry analysis of paraffin-embedded mouse Cecal Tissue using alpha Smooth Muscle Actin antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Western blot analysis of alpha Smooth Muscle Actin in αSmooth Muscle Actin in rat Brain, MCF-7, C6 and 3T3 lysates using alpha Smooth Muscle Actin antibody, Western blot analysis of alpha Smooth Muscle Actin in Hela, A549, HL6, U2OS, C6 lysates using alpha Smooth Muscle Actin antibody
Alternative Name: ACTA2; ACTSA; ACt VS; GIG46; Actin; aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein; α-SMA
Immunogen: Synthetic Peptide of α-SMA
Conjugate: Unconjugated
Modification: Unmodified