Alpha-tubulin Monoclonal Antibody (8F11) - BT-MCA0085

Alpha-tubulin Monoclonal Antibody (8F11)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0085-20, BT-MCA0085-50, BT-MCA0085-100

Citations, Manuals and MSDS Available upon request.

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.

Research Areas: Tags and; cell markers; Signal transduction

Target Protein: TUBA1A

Applications: WB, IHC-p, IF, ICC, IP

Reactivity: Human,Rat,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Tubulin alpha-1A chain

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 50136

UniProt Accession: Human: Q71U36; P68363P68370; Q6P9V9

GeneID: Human: 7846; 10376; Mouse: 22142; 22143; Rat: 64158; 500929

Research Use Only