ALS2CR4 rabbit pAb - ES7213

ALS2CR4 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7213-50, ES7213-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a tetraspanin protein that is thought to be involved in WNT signaling. Defects in this gene are a cause of Joubert syndrome-14. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],

Alternate Name: TMEM237; ALS2CR4; Transmembrane protein 237; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human ALS2CR4. AA range:181-230

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 48kD

Human Gene ID: 65062

Human SWISS Prot NO: Q96Q45

Subcellular Location: Membrane; Multi-pass membrane protein. Cell projection, cilium. Localizes at the proximal region of primary cilia were observed, consistent with localization to the transition zone. Anchored to the transition zone by RPGRIP1L.

Research Use Only