AMACR Monoclonal Antibody (4A12) - RA10755

AMACR Monoclonal Antibody (4A12)

Size: 50μL, 100μL

Catalogue Numbers: RA10755-50, RA10755-100

Citations, Manuals and MSDS Available upon request.

Background: alpha-methylacyl-CoA racemase (AMACR) Homo sapiens This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R) - and (S) -stereoisomers. The conversion to the (S) -stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011],

Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IF/ICC; IHC-p

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 23600

Protein MW (KDa): 42

SWISS: Q9UHK6

Source: Mouse

Research Use Only