AMD Polyclonal Antibody - BT-AP14196

AMD Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14196-20, BT-AP14196-50, BT-AP14196-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Research Areas: Neuroscience; Signal transduction

Target Protein: PAM

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Peptidyl-glycine alpha-amidating monooxygenase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P19021; Mouse: P97467; Rat: P14925

Synonyms: Peptidyl-glycine alpha-amidating monooxygenase;PAM [Includes: Peptidylglycine alpha-hydroxylating monooxygenase;PHM;EC 1.14.17.3; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase;EC 4.3.2.5

GeneID: Human: 5066

Research Use Only