AMGO2 Polyclonal Antibody - BT-AP14198

AMGO2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14198-20, BT-AP14198-50, BT-AP14198-100

Citations, Manuals and MSDS Available upon request.

Background: Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.,Belongs to the immunoglobulin superfamily. AMIGO family.,Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,Contains 6 LRR (leucine-rich) repeats.,subcellular location:Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons.,subunit:Binds itself as well as AMIGO1 and AMIGO3.,tissue specificity:Highest levels in breast, ovary, cervix, and uterus. Lower levels in lung, colon, and rectum. Differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers.,

Research Areas: Neuroscience

Target Protein: AMIGO2

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Amphoterin-induced protein 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q86SJ2; Mouse: Q80ZD9; Rat: Q7TNJ4

Synonyms: Amphoterin-induced protein 2;AMIGO-2;Alivin-1;Differentially expressed in gastric adenocarcinomas;DEGA

GeneID: Human: 347902

Research Use Only