AMPD3 Polyclonal Antibody - BT-AP00409

AMPD3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00409-20, BT-AP00409-50, BT-AP00409-100

Citations, Manuals and MSDS Available upon request.

Background: AMPD3 encodes a member of the AMP deaminase gene family. The adenosine monophosphate deaminase 3 is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Research Areas: Cardiovascular

Target Protein: AMPD3

Applications: IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: AMPD3 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 88812

UniProt Accession: Human: Q01432; Mouse: O08739; Rat: O09178

Synonyms: AMPD3; AMP deaminase 3; AMP deaminase isoform E; Erythrocyte AMP deaminase

GeneID: Human: 272; Mouse: 11717; Rat: 25095

Research Use Only