AMPKβ2 Mouse Monoclonal Antibody (Mix-mA) - RA10769

AMPKβ2 Mouse Monoclonal Antibody (Mix-mA)

Size: 50μL, 100μL

Catalogue Numbers: RA10769-50, RA10769-100

Citations, Manuals and MSDS Available upon request.

Background: protein kinase AMP-activated non-catalytic subunit beta 2 (PRKAB2) Homo sapiens The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK) . AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.42% sodium azide.

Storage Instructions: -20°C/1 year

Applications: IHC-p; WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 5565

Protein MW (KDa): 30

SWISS: O43741

Source: Mouse

Research Use Only