Product Description

AMPKβ2 Mouse Monoclonal Antibody (Mix-mA)

Sizes: 50μL, 100μL

Catalogue Numbers: RA10769-50, RA10769-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: protein kinase AMP-activated non-catalytic subunit beta 2 (PRKAB2) Homo sapiens The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013],

Reactivity: Human, Mouse, Rat

Host: Mouse

Applications: IHC-p, WB

Alternate Names: 5'-AMP-activated protein kinase subunit beta-2 (AMPK subunit beta-2)

Clonality: Monoclonal

Dilution: IHC-p1:50-200, WB 1:1000-2000

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.42% sodium azide.

Human Gene ID: 5565

Protein Molecular Weight（KDa): 30

Molecular Weight: 30

Research Use Only