AMPK gamma1 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-14562-60, E-AB-14562-120, E-AB-14562-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: PRKAG1
Target Synonym: 5' AMP activated protein kinase gamma 1 subunit; 5' AMP activated protein kinase subunit gamma 1; 5''-AMP-activated protein kinase subunit gamma-1; AAKG1; AMP activated protein kinase noncatalytic gamma 1 subunit; AMPK gamma 1 chain; AMPK gamma1; AMPK subunit gamma-1; AMPKg; MGC8666; PRKAG 1; PRKAG1; Protein kinase AMP activated gamma 1 non catalytic subunit; protein kinase; AMP-activated; noncatalytic gamma-1
Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P54619
Background: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Concentration: 0.1 mg/mL
Immunogen: Recombinant protein of human PRKAG1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:200-1:1000
Calculated MW: 38kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only