AMPM1 Polyclonal Antibody - BT-AP06247

AMPM1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP06247-20, BT-AP06247-50, BT-AP06247-100

Citations, Manuals and MSDS Available upon request.

Background: Catalytic activity:Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.,cofactor:Binds 1 sodium ion per subunit. The sodium ion has a structural role.,cofactor:Binds 2 cobalt ions per subunit.,cofactor:Binds 2 cobalt ions per subunit. The true nature of the physiological cofactor is under debate. The enzyme is also active with zinc, manganese or divalent iron ions.,Removes the amino-terminal methionine from nascent proteins.,Removes the amino-terminal methionine from nascent proteins. Required for normal progression through the cell cycle.,Belongs to the peptidase M24A family.,

Research Areas: Metabolism; Signal transduction

Target Protein: METAP1

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Methionine aminopeptidase 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P53582; Mouse: Q8BP48

Synonyms: Methionine aminopeptidase 1;MAP 1;MetAP 1;EC 3.4.11.18;Peptidase M 1

GeneID: Human: 23173

Research Use Only