Ang-1 Polyclonal Antibody - BT-AP00440

Ang-1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00440-20, BT-AP00440-50, BT-AP00440-100

Citations, Manuals and MSDS Available upon request.

Background: ANGPT1 encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The angiopoietin 1 encoded by ANGPT1 is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Research Areas: Cardiovascular; Cancer

Target Protein: ANGPT1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Ang-1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 57513

UniProt Accession: Human: Q15389; Mouse: O08538; Rat: O35460

Synonyms: ANGPT1; KIAA0003; Angiopoietin-1; ANG-1

GeneID: Human: 284; Mouse: 11600; Rat: 89807

Research Use Only