ANG I rabbit pAb - ES4273

ANG I rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4273-50, ES4273-100

Citations, Manuals and MSDS Available upon request.

Background: angiogenin (ANG) Homo sapiens The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Aug 2014],

Alternate Name: ANG; RNASE5; Angiogenin; Ribonuclease 5; RNase 5

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human N-ternal ANG. AA range:11-60

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 17kD

Human Gene ID: 283

Human SWISS Prot NO: P03950

Subcellular Location: Cytoplasmic vesicle, secretory vesicle lumen. Secreted. Nucleus. Nucleus, nucleolus. Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA (PubMed:12051708).

Research Use Only