Product Description

ANG Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60510-50, BS60510-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Angiogenesis is defined as the process of neovascμlarization and formation of new blood vessels from the established micro-circμlation. Angiogenin (ANG or ANG I) is a non-glycosylated polypeptide, 123 amino acids in length, whose function is central to this process. ANG I shows a high degree of homology with known ribonucleases such as pancreatic ribonuclease A, and the capacity of ANG I to induce blood vessel growth is critically dependent on its ribonucleolytic activity. ANG I is thought to be involved in the development of solid tumors, and ANG I antagonists are capable of inhibiting tumor growth. By a poorly understood mechanism, ANG I is endocytosed by subconfluent endothelial cells and translocated to the nucleus where it accumμlates in the nucleolus. The ANG I receptor has not yet been identified.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: IHC

Alternate Names: Angiogenin, Ribonuclease 5, RNase 5, ANG, RNASE5

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human ANG

Dilution: IHC:1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: ANG polyclonal antibody detects endogenous levels of ANG protein.

Molecular Weight: ~ 17 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P03950

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only