Angiomotin-L1 Polyclonal Antibody - BT-AP00442

Angiomotin-L1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00442-20, BT-AP00442-50, BT-AP00442-100

Citations, Manuals and MSDS Available upon request.

Background: Angiomotin-like protein 1 encoded by AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene.

Research Areas: Signal Transduction; Cardiovascular

Target Protein: AMOTL1

Applications: IHC-p, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Angiomotin-L1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 106574

UniProt Accession: Human: Q8IY63; Mouse: Q9D4H4

Synonyms: AMOTL1; Angiomotin-like protein 1

GeneID: Human: 154810; Mouse: 75723

Research Use Only