Angiopoietin 1 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90054-50, BS90054-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q15389(Human) O35460(Rat)
Host: Rabbit
Reactivity: Human, Rat
Applications: WB
All Applications: WB:1:1,000-1:2,000
Background: Tie-1 and Tie-2 (also designated Tek) are novel cell surface receptor tyrosine kinases. The extracellular domain of Tie-1 has an unusual multidomain structure consisting of a cluster of three epidermal growth factor homology motifs localized between two immunoglobulin-like loops, which are followed by three fibronectin type III repeats next to the transmembrane region. Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2. Preliminary biochemical analyses of Ang-1 reveal a potential fibrinogen-like domain at the carboxy terminus and coiled-coil regions in the amino terminus. Ang-1 is an angiogenic factor that is thought to be involved in endothelial development. A related protein, angiopoietin-2 (Ang-2), has been identified as a naturally occurring antagonist of Ang-1 activation of Tie-2. In adult tissue, Ang-2 expression seems to be restricted to sites of vascular remodeling.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Angiopoietin 1 on K562 cellsLysates using anti-Angiopoietin 1 antibody at 1/1,000 dilution.
Bioworld Molecular Weight: 57 kDa
Specificity: Angiopoietin 1 polyclonal antibody detects endogenous levels of Angiopoietin 1 protein.
Alternative Name: ANG-1, ANGPT1, AGP 1, AGP1, AGPT, ANG 1, ANG, ANG-1, ANG1, Angiopoietin-1, Angiopoietin1, ANGP1, ANGPT 1, Angpt1, KIAA0003, OTTHUMP00000227592, OTTHUMP00000227599, OTTHUMP00000227600,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified