Angiopoietin Like 4 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB10540-50, MB10540-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: Q9BY76
Host: Rabbit
Reactivity: Human
Applications: WB
All Applications: WB: 1/500-1/1000
Background: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation .
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Angiopoietinlike 4 in K562, HelaLysates using Angiopoietin Like 4 antibody.
Bioworld Molecular Weight: Calculated MW: 45 kDa; Observed MW: 55 kDa
Specificity: IgG
Alternative Name: NL2; ARP4; FIAF; HARP; PGAR; HFARP; TGQTL; UNQ171; pp1158
Immunogen: Recombinant protein of human Angiopoietin-like 4
Conjugate: Unconjugated
Modification: Unmodified