Angptl7 (P346) Polyclonal Antibody
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Catalogue Numbers: BS3809-50, BS3809-100
Sizes: 50µl, 100µl
Swiss-Prot: O43827
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC
Background: Angptl7 (angiopoietin-like 7), alternately known as cornea-derived transcript 6 protein (CDT6) or AngX, is a 346 amino acid secreted protein that is expressed specifically in the stromal layer of cornea. Angptl7 forms disulfide-linked homotetramers via coiled-coil interactions and contains one fibrinogen C-terminal domain. Overexpressed in patients with glaucoma, Angptl7 serves as a potential therapeutic target for glaucoma and has been found to increase collagen expression. The gene encoding Angptl7 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Specificity: Angptl7 (P346) polyclonal antibody detects endogenous levels of Angptl7 protein.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of Angptl7 (P346) pAb at 1:1000 dilution
Lane 1: H9C2 whole cell lysate (40ug)
Lane 2: CT26 whole cell lysate (40ug)
Lane 3: Hela whole cell lysate (40ug)
Lane 4: MCF-7 whole cell lysate (20ug), Immunohistochemistry (IHC) analyzes of Angptl7 (P346) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.
Bioworld Molecular Weight: ~ 40 kDa
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Alternative Name: Angiopoietin-related protein 7; Angiopoietin-like factor; Angiopoietin-like protein 7; Cornea-derived transcript 6 protein; ANGPTL7; CDT6; ORF Names: UNQ313/PRO356
Immunogen: Synthetic peptide, corresponding to amino acids 321-370 of Human Angptl7.
Conjugate: Unconjugated
Modification: Unmodified