ANKMY2 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-14569-60, E-AB-14569-120, E-AB-14569-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: ANKMY2
Target Synonym: Ankmy2; ANKY2; Ankyrin repeat and MYND domain containing 2; Ankyrin repeat and MYND domain containing protein 2; Ankyrin repeat and MYND domain-containing protein 2; DKFZP564O043; OTTHUMP00000116019; OTTHUMP00000201684; ZMYND20
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q8IV38
Background: ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states.
Concentration: 0.2 mg/mL
Immunogen: Recombinant protein of human ANKMY2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:100
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only