Annexin IV Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90061-50, BS90061-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P09525(Human)
Host: Rabbit
Reactivity: Human
Applications: WB, ICC, IF, IHC, FC
All Applications: WB:1:500-1:2,000
ICC/IF:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Background: The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain which binds to phospholipids in a Ca++-dependent manner and a unique amino terminal region which may confer binding specificity. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. For example, the crystal structure of Annexin III has suggested a hydrophilic amino terminus with possible Ca++ channel activity. Similarly, Annexin V has ion channel properties. Annexin IV, also referred to as endonexin, functions to regulate Cl- flux by mediating calmodulin kinase II (CaMKII) activity and Annexin V has been shown to regulate PKC activity.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: Annexin IV polyclonal antibody detects endogenous levels of Annexin IV protein.
Bioworld Molecular Weight: 36 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Annexin IV on human liver tissue lysate using anti-Annexin IV antibody at 1/2,000 dilution., ICC staining Annexin IV in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: PAP-II, ANXA4, ANX4, 35 beta calcimedin, 35-beta calcimedin, AIV, Annexin 4, Annexin A4, Annexin IV (placental anticoagulant protein II), Annexin IV, Annexin IV placental anticoagulant protein II, Annexin-4, AnnexinA4, AnnexinIV, ANX 4, ANX A4, ANX4, ANXA 4, ANXA4, ANXA4 protein, ANXA4, Carbohydrate binding protein P33/P41, Carbohydrate-binding protein p33/p41, Chromobindin 4, Chromobindin-4, Chromobindin4, DKFZp686H02120, Endonexin I, EndonexinI, Lipocortin IV, LipocortinIV, MGC75105, OTTHUMP00000160052, OTTHUMP00000202207, P32.5, P33/41, PAP II, PAP-II, PAPII, PIG 28, PIG28, Placental anticoagulant protein II, PP4 X, PP4-X, PP4X, Proliferation inducing gene 28, Proliferation inducing protein 28, Protein II, Xanx-4, ZAP 36, ZAP36,
Immunogen: Recombinant protein within human Annexin IV aa 1-200.
Conjugate: Unconjugated
Modification: Unmodified