ANP32C Polyclonal Antibody
Catalogue Numbers: BS5864-50, BS5864-100
Sizes: 50µl, 100µl
Alternative Name: Acidic leucine-rich nuclear phosphoprotein 32 family member C; Phosphoprotein 32-related protein 1; Tumorigenic protein pp32r1; PP32R1
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: O43423
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: ANP32C (acidic (leucine-rich) nuclear phosphoprotein 32 family, member C), also known as PP32R1 (phosphoprotein 32-related protein 1) or tumorigenic protein pp32r1, is a 234 amino acid protein that contains 4 leucine-rich repeats and belongs to the ANP32 family. ANP32C shares 87.7% amino acid sequence identity with ANP32A, a tumor suppressor that inhibits a variety of cancers, such as prostate and breast cancers. Although similar to ANP32A, ANP32C is tumorigenic and is expressed in activated stem cells, such as mobilized CD34+ cells and cord blood CD34+ cells, but not in resting bone marrow CD34+ cells. ANP32C is also expressed in a variety of neoplastic cell lines, mainly in prostatic adenocarcinoma cell lines, but not in normal protastic tissue, and may also modulate the oncogenic potential of human prostate cancer.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ANP32C polyclonal antibody detects endogenous levels of ANP32C protein.
Bioworld Molecular Weight: ~ 27 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of ANP32C polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: sp2/0 cell lysate
Lane 3: H9C2 cell lysate
Immunogen: Synthetic peptide, corresponding to amino acids 161-206 of Human ANP32C.
Conjugate: Unconjugated
Modification: Unmodified