ANPRB Polyclonal Antibody - BT-AP06287

ANPRB Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP06287-20, BT-AP06287-50, BT-AP06287-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.

Research Areas: Cardiovascular; Neuroscience; Signal transduction

Target Protein: NPR2

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Atrial natriuretic peptide receptor 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P20594; Mouse: Q6VVW5; Rat: P16067

Synonyms: Atrial natriuretic peptide receptor 2;EC 4.6.1.2;Atrial natriuretic peptide receptor type B;ANP-B;ANPR-B;NPR-B;Guanylate cyclase B;GC-B

GeneID: Human: 4882

Research Use Only