ANR28 Polyclonal Antibody - BT-AP06288

ANR28 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP06288-20, BT-AP06288-50, BT-AP06288-100

Citations, Manuals and MSDS Available upon request.

Background: Putative regulatory subunit of protein phospatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation.,Contains 27 ANK repeats.,subcellular location:Seems to be excluded from nucleoli.,subunit:Protein phospatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP1C and HNRPK. Interacts with PPP6C, SAPS1 and SAPS3.,

Research Areas: Cell biology; Epigenetics and nuclear signaling; Signal transduction

Target Protein: ANKRD28

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O15084; Mouse: Q505D1

Synonyms: Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A;PP6-ARS-A;Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A;Ankyrin repeat domain-containing protein 28;

GeneID: Human: 23243

Research Use Only