Anti-Covid-19 N protein mAb IgG(06FC) - BT-CV00001

Anti-Covid-19 N protein mAb IgG(06FC)

Sizes: 100μg, 1mg

Catalogue Number: BT-CV00001-100μg, BT-CV00001-1mg

Citations, Manuals and MSDS Available upon request.

Background: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways . Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. COVID-19 antibodies can be produced by a host immune system following exposure to SARS-CoV-2. IgG and IgM antibodies are also known as immunoglobulins IgG and IgM, respectively, and are among the antibody isotypes produced by vertebrate immune systems.

Research Areas: Others

Target Protein: SARS-CoV-2 N, 2019-nCoV N, Covid-19 N

Applications: WB,ELISA

Reactivity: Covid-19

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: SARS-CoV-2 Nucleoprotein , 2019-nCoV Nucleoprotein, Covid-19 Nucleoprotein

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Synonyms: SARS-CoV-2 Nucleoprotein , 2019-nCoV Nucleoprotein, Covid-19 Nucleoprotein

Research Use Only