Anti-Eculizumab Polyclonal Antibody - AF687014

Anti-Eculizumab Polyclonal Antibody

Sizes: 50μg, 100μg

Catalogue Numbers: AF687014-50, AF687014-100

Citations, Manuals and MSDS Available upon request.

Host species: Rabbit

Specificity: The product is specific for Eculizumab. This antibody serves as an excellent positive control for Eculizumab immunogenicity (ADA) assays.

Immunogen: Eculizumab

Form: Liquid

Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Clonality: Polyclonal

Isotype: IgG

Applications: ELISA

Target: Rabbit polyclonal to Soliris.

Purification: Purified by antigen affinity column.

Stability and Storage: The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.

Background: Eculizumab with trade name Soliris, is an FDA-approved drug to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and neuromyelitis optica. Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5. Eculizumab specifically binds to the terminal complement component 5, or C5. Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions.

Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.