Product Description

ANTXR1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS71922-50, BS71922-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellμlar processes. Three alternatively spliced variants that encode different protein isoforms have been described.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IF

Alternate Names: ATR, GAPO, TEM8

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein of human ANTXR1

Dilution: WB 1:500 - 1:2000
IF 1:50 - 1:100

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: ANTXR1 polyclonal antibody detects endogenous levels of ANTXR1 protein.

Molecular Weight: 75kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9H6X2

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only