APBA1 Polyclonal Antibody - BT-AP06326

APBA1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP06326-20, BT-AP06326-50, BT-AP06326-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimerandapos;s disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimerandapos;s disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.

Research Areas: Neuroscience

Target Protein: APBA1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Amyloid beta A4 precursor protein-binding family A member 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q02410; Mouse: B2RUJ5; Rat: O35430

Synonyms: Amyloid beta A4 precursor protein-binding family A member 1;Adapter protein X11alpha;Neuron-specific X11 protein;Neuronal Munc18-1-interacting protein 1;Mint-1

GeneID: Human: 320

Research Use Only