APC Anti-Human CD184/CXCR4 Antibody [12G5]
Sizes: 20 Tests, 100 Tests, 100 Tests×2
Catalogue Numbers: E-AB-F1157E-20, E-AB-F1157E-100, E-AB-F1157E-100×2
Citations, Manuals and MSDS Available upon request.
Abbreviation: CD184
Target Synonym: FB22, Fusin, HM89, LCR1, LAP-3,
Conjugation: APC
Host: Mouse
Species Reactivity: Human
Application: FCM
Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Isotype: Mouse IgG2a, κ
Clone No.: 12G5
UNIProt ID: P61073
Background: CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2.
Concentration: 5 μL/Test
Control Catalogue Number: E-AB-F09802E
Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
GeneID: 7852
Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping: Ice bag
Research Use Only