APC Anti-Human CD273/PD-L2 Antibody [24F.10C12] - E-AB-F1175E

APC Anti-Human CD273/PD-L2 Antibody [24F.10C12]

Sizes: 20 Tests, 100 Tests, 100 Tests×2

Catalogue Numbers: E-AB-F1175E-20, E-AB-F1175E-100, E-AB-F1175E-100×2

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD273/PD-L2

Target Synonym: B7DC, CD273, PDCD1L2, PDL2,

Conjugation: APC

Host: Mouse

Species Reactivity: Human

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Isotype: Mouse IgG2a, κ

Clone No.: 24F.10C12

UNIProt ID: Q9BQ51

Background: CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.

Concentration: 5 μL/Test

Control Catalogue Number: E-AB-F09802E

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 80380

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Shipping: Ice bag

Research Use Only