APC Anti-Human CD279/PD-1 Antibody [EH12.2H7] - E-AB-F1229E

APC Anti-Human CD279/PD-1 Antibody [EH12.2H7]

Sizes: 20 Tests, 100 Tests, 100 Tests×2

Catalogue Numbers: E-AB-F1229E-20, E-AB-F1229E-100, E-AB-F1229E-100×2

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD279/PD-1

Target Synonym: PDCD1, PD1, Protein PD-1, hPD-1,

Conjugation: APC

Host: Mouse

Species Reactivity: Human

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Isotype: Mouse IgG1, κ

Clone No.: EH12.2H7

UNIProt ID: Q15116

Background: Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.

Concentration: 5 μL/Test

Control Catalogue Number: E-AB-F09792E

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 5133

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Shipping: Ice bag

Research Use Only