Product Description

APC5 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21965-50, RA21965-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: anaphase promoting complex subunit 5 (ANAPC5) Homo sapiens This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: ANAPC5, APC5, Anaphase-promoting complex subunit 5, APC5, Cyclosome subunit 5

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight: 85

Protein Molecular Weight (kDa): 85

Storage: -20°C/1 year

Human Gene ID: 51433

Human SwissProt Number: Q9UJX4

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only