APC5 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA21965-50, RA21965-100
Citations, Manuals and MSDS Available upon request.
Background: anaphase promoting complex subunit 5 (ANAPC5) Homo sapiens This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Alternative Names: ANAPC5; APC5; Anaphase-promoting complex subunit 5; APC5; Cyclosome subunit 5
Applications: WB; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 51433
Protein MW (KDa): 85
SWISS: Q9UJX4
Source: Rabbit
Research Use Only