APLP-1 rabbit pAb - ES3788

APLP-1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3788-50, ES3788-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

Alternate Name: APLP1; Amyloid-like protein 1; APLP; APLP-1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from APLP-1 . at AA range: 360-440

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 72kD

Human Gene ID: 333

Human SWISS Prot NO: P51693

Subcellular Location: Cell membrane; Single-pass type I membrane protein.; [C30]: Cytoplasm. C-terminally processed in the Golgi complex.

Research Use Only