APLP-2 (Y274) Polyclonal Antibody-BS3808

APLP-2 (Y274) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS3808-50, BS3808-100

Sizes: 50µl, 100µl

Swiss-Prot: Q06481

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

Background: APLP1 (amyloid precursor-like protein 1) is a protein whose predicted amino acid sequence is 42% identical and 64% similar to that of the amyloid beta protein precursor (APP).APLP2 is a human sperm membrane protein which contains a segment with high homology to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: APLP-2 (Y274) polyclonal antibody detects endogenous levels of APLP-2 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of APLP-2 (Y274) pAb in paraffin-embedded human lung carcinoma tissue at 1:50,showing cell membrane and nuclear staining.Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Bioworld Molecular Weight: ~ 87 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Amyloid-like protein 2; APLP 2; APPH; Amyloid protein homolog; CDEI box-binding protein; CDEBP; APLP2; APPL2

Immunogen: Synthetic peptide, corresponding to amino acids 250-300 of Human APLP-2.

Conjugate: Unconjugated

Modification: Unmodified