ApoB (Apolipoprotein B nano antibody Sizes: 50μL, 100μL Catalogue Numbers: RA20455-50, RA20455-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: apolipoprotein B (APOB) Homo sapiens This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008], Reactivity: Human, Mouse Host: Camel Applications: FCM, ELISA Alternate Names: APOB, Apolipoprotein B-100, Apo B-100 Clonality: Polyclonal Dilution: ELISA 1:10000-20000 Storage: -20°C/1 year Human Gene ID: 338 Human SwissProt Number: P04114 Condition: Liquid in PBS Research Use Only