ApoB Monoclonal Antibody - RA10792

ApoB Monoclonal Antibody Size: 50μL, 100μL Catalogue Numbers: RA10792-50, RA10792-100 Citations, Manuals and MSDS Available upon request. Background: apolipoprotein B (APOB) Homo sapiens This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008], Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol. Storage Instructions: -20°C/1 year Applications: WB; IF/ICC; FCM; ELISA Species Cross-Reactivity: Human GeneID (Human): 338 SWISS: P04114 Source: Mouse Research Use Only