Apoe Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A27419-20, A27419-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the apolipoprotein A1/A4/E family of proteins. This protein is involved in the transport of lipoproteins in the blood. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Homozygous knockout mice for this gene accumulate high levels of cholesterol in the blood and develop atherosclerosis. Different alleles of this gene have been associated with either increased risk or a protective effect for Alzheimer's disease in human patients. This gene maps to chromosome 7 in a cluster with the related apolipoprotein C1, C2 and C4 genes.
Category: Polyclonal Antibodies
Applications: WB, IF-P, IHC-P, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 36kDa
Observed Molecular Weight: 35kDa
Immunogen: Recombinant protein (or fragment) .
Species: Mouse
GeneID: 11816
SWISS: P08226
Alternate Names: Apo-E
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:4000 IF-P, 1:100 - 1:400 IHC-P, 1:200 - 1:800 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cholesterol metabolism, host-virus interaction, lipid metabolism, lipid transport, steroid metabolism, sterol metabolism, transport, heparin binding
NCBI Alias: Apoe
Research Use Only