Product Description

APPL Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10560-50, MB10560-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9UKG1

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 80 kDa; Observed MW: 80 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of APPL in rat Brain, C6, 3T3, Hela lysates using APPL antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using APPL antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Alternative Name: APPL1; APPL; DIP13A; KIAA1428; DCC-interacting protein 13-alpha; Dip13-alpha; Adapter protein containing PH domain; PTB domain and leucine zipper motif 1

Immunogen: A synthetic peptide of human APPL

Conjugate: Unconjugated

Modification: Unmodified