APRIL Polyclonal Antibody - BT-AP00548

APRIL Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00548-20, BT-AP00548-50, BT-AP00548-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. This protein (tumor necrosis factor superfamily member 13) is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of TNFSF13 have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.

Research Areas: Immunology

Target Protein: TNFSF13

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: APRIL Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 27433

UniProt Accession: Human: O75888; Mouse: Q9D777

Synonyms: TNFSF13; APRIL; TALL2; ZTNF2; Tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death

GeneID: Human: 8741; Mouse: 69583

Research Use Only