APS Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA22004-50, RA22004-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: SH2B adaptor protein 2 (SH2B2) Homo sapiens The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq, Jun 2009], Reactivity: Human, Mouse, Rat Host: Rabbit Applications: WB, ELISA Alternate Names: SH2B2, APS, SH2B adapter protein 2, Adapter protein with pleckstrin homology and Src homology 2 domains, SH2 and PH domain-containing adapter protein APS Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. Molecular Weight: 67 Protein Molecular Weight (kDa): 67 Storage: -20°C/1 year Human Gene ID: 10603 Human SwissProt Number: O14492 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only