AQP4 Polyclonal Antibody - BT-AP00558

AQP4 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00558-20, BT-AP00558-50, BT-AP00558-100

Citations, Manuals and MSDS Available upon request.

Background: AQP4 encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein (aquaporin 4) is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Research Areas: Signal Transduction; Metabolism

Target Protein: AQP4

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: AQP4 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 34830

UniProt Accession: Human: P55087; Mouse: P55088; Rat: P47863

Synonyms: AQP4; Aquaporin-4; AQP-4; Mercurial-insensitive water channel; MIWC; WCH4

GeneID: Human: 361; Mouse: 11829; Rat: 25293

Research Use Only