Aquaporin 3 Polyclonal Antibody-BS67167

Aquaporin 3 Polyclonal Antibody

Catalogue Numbers: BS67167-50, BS67167-100

Sizes: 50µl, 100µl

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: Q92482

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Water channel required to promote glycerol permeability and water transport across cell membranes (PubMed:12239222, PubMed:30420639).
Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism (By similarity).

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 128% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of Aquaporin 3 protein.

Extra Notes: Western blot analysis of Aquaporin 3 expression in mouse kidney (A), rat kidney (B) whole cell lysates.

Bioworld Molecular Weight: ~ 34 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Aquaporin-3; AQP-3; Aquaglyceroporin-3

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Aquaporin 3. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified