Aquaporin-4 (AQP4) Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2887-20, A2887-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. Additional isoforms, resulting from the use of alternative in-frame translation initiation codons, have also been described. Recent studies provided evidence for translational readthrough in this gene, and expression of C-terminally extended isoforms via the use of an alternative in-frame translation termination codon.
Category: Polyclonal Antibodies
Applications: WB, IF-P, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 35kDa
Observed Molecular Weight: 35kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 361
SWISS: P55087
Alternate Names: MIWC; WCH4; hAQP4; Aquaporin-4 (AQP4)
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:100 - 1:500 IF-P, 1:50 - 1:200 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Neuroscience, Neurodegenerative Diseases Markers, Other Neurological disorders.
NCBI Alias: AQP4
Research Use Only