Product Description

ARC Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS79195-50, BS79195-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Master regμlator of synaptic plasticity that self-assembles into virion-like capsids that encapsμlate RNAs and mediate intercellμlar RNA transfer in the nervous system. ARC protein is released from neurons in extracellμlar vesicles that mediate the transfer of ARC mRNA into new target cells, where ARC mRNA can undergo activity-dependent translation. ARC capsids are endocytosed and are able to transfer ARC mRNA into the cytoplasm of neurons. Acts as a key regμlator of synaptic plasticity: required for protein synthesis-dependent forms of long-term potentiation (LTP and depression (LTD and for the formation of long-term memory.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Alternate Names: ARC, Arg3.1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human ARC(NP_056008.1).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Unmodification

Molecular Weight: 45kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q7LC44

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only