Arginase I rabbit pAb - ES6028

Arginase I rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6028-50, ES6028-100

Citations, Manuals and MSDS Available upon request.

Background: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

Alternate Name: ARG1; Arginase-1; Liver-type arginase; Type I arginase

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human ARG1. AA range:61-110

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 35kD

Human Gene ID: 383

Human SWISS Prot NO: P05089

Subcellular Location: Cytoplasm. Cytoplasmic granule. Localized in azurophil granules of neutrophils (PubMed:15546957).

Research Use Only